CAIRO — A drone strike has shut down a crucial Saudi oil pipeline and could leave most of the system out of service for three to five weeks, according to two regional officials briefed on the repairs. The attack Thursday damaged the East-West Pipeline, including a major pumping facility, forcing Saudi authorities to halt operations. One official said portions of the 745-mile pipeline might continue operating during repairs, but the amount of oil that could move through the system remains uncertain. The pipeline carries Saudi crude from ports on the Persian Gulf across the country to Yanbu on the Red Sea. That route has become especially important as attacks linked to the war with Iran have disrupted shipping through the Strait of Hormuz, the only maritime exit from the Persian Gulf. Saudi Arabia blamed the pipeline strike on drones launched by Iranian-backed militias in Iraq. The officials did not provide additional details about the damage or identify a specific repair timetable beyond the three-to-five-week estimate. Oil prices rose more than 2% Monday as traders assessed the potential effect on global supplies. Saudi Arabia is the world’s largest oil exporter, and the pipeline’s reduced capacity could make it more difficult for the kingdom to move crude to overseas buyers while Gulf shipping remains constrained. The supply concerns are unfolding alongside a widening threat to Red Sea trade. Yemen’s Houthi rebels, who are backed by Iran, have seized additional islands along key shipping routes, adding pressure to a corridor already affected by regional conflict. The developments highlight the vulnerability of major energy infrastructure and shipping lanes to attacks by armed groups. For households and businesses far from the conflict zone, prolonged disruptions could contribute to higher fuel and transportation costs, depending on how long the outages last and whether other producers can offset the lost flows.