The Kentucky Transportation Cabinet said the closures will affect I-65 North and South at mile marker 116, the stretch that crosses the Salt River. Work is scheduled to begin at 9 a.m. and continue until 10 p.m.

Crews will tackle the northbound side first before shifting to the southbound lanes, according to the cabinet. That sequencing means the heaviest impacts could vary by time of day, with morning and early afternoon traffic bearing the brunt on the northbound side and evening travelers facing restrictions on the southbound side.

With two of three lanes closed in each direction, the highway will be reduced to a single lane through the work zone. Transportation officials are urging motorists to slow down, stay alert and allow extra time for trips through the area. Backups are likely during peak commuting hours, and drivers may want to consider alternate routes where possible.

The repairs come as part of routine pavement maintenance on one of the region's most heavily traveled corridors. The Salt River bridge area has seen ongoing upkeep in recent years, and Monday's work is aimed at addressing deteriorating pavement before it worsens.

For updates on traffic conditions, drivers can check the state's traffic and travel information systems before heading out. Officials remind motorists that work zones are especially dangerous for roadside crews and that reduced speeds and increased following distance are essential.

This story will be updated if the schedule changes or additional lane restrictions are announced.